With insufficiency (hypovitaminosis) lipoic acid, the following health problems can occur:
Neurological disorders, convulsions;
Development of hypertension;
Disturbance of bile formation;
Propensity to fatty liver degeneration.
Daily requirement of vitamin N
The daily requirement of alpha-lipoic acid is:
Adult people with normal health 25-50 mg;
Children 12,5-25 mg;
Pregnancy and lactation (with caution and after consulting a doctor) up to 75 mg.
With various diseases, therapeutic doses increase to 75-1200 mg day, depending on the disease and destination.
The daily dose is increased when:
Constant fatigue, heavy physical and mental work, violation of concentration;
Various diseases atherosclerosis, diabetes, HIV infection, Alzheimer’s disease, hepatitis, cirrhosis, obesity;
Poisoning the body with alcohol, food.
Dosages of lipoic acid
The medicinal form of vitamin N “Tyoktatsid” is administered intravenously (intravenously), intramuscularly (in m), orally.
Severe forms of polyneuropathies IV slowly (not more than 50 mg min), 600 mg or IV dropwise, 0.9% NaCl solution 1 time day, for 2-4 weeks. In severe forms, the dose is increased to 1200 mg. Intramuscular (IM) dose (injection) in one place should not exceed 50 mg. Further treatment is accompanied by oral administration of the drug for 3 months.
Important! Remember, “Tioktatsid” is a medicinal product, so take it only after consulting a doctor.
Side effects of taking a lipoic acid dosage form
Side effects of taking a lipoic acid dosage form Among the side effects of taking chemical analogs of amygdalin, one can distinguish:
- Allergic reaction skin itching, hives, anaphylactic shock;
Hemorrhagic rash (purpura);
Spot hemorrhages, thrombocytopathy, thrombophlebitis;
Increased intracranial pressure (with rapid administration);
Overdose (hypervitaminosis) by the drug form of lipoic acid
An overdose of chemical analogues of thioctic and lipoic acid may lead to such symptoms as:
Violations of blood clotting;
Violations of the acid balance (increased acidity) with lactic acidosis;
With the above symptoms, it is necessary to induce vomiting, rinse the stomach, take a sorbent (“Activated Carbon”, “Enterosgel”). If necessary, consult a doctor.
When vitamin N comes from natural sources, it is excreted from the body without side effects.
Sources of vitamin N (lipoic acid)
Sources of vitamin N (lipoic acid) Vegetable sources of lipoic acid: spinach, yeast, beans, rice, wheat, cabbage, mushrooms, in small doses vegetables and fruits.
Animal sources: liver, heart, kidneys, beef, milk, butter, sour cream, cream, cottage cheese, kefir, eggs
Chemical sources: “Tioktatsid”, “Lipoat”, “Lipoic acid”.
Synthesis in the body: in the body, vitamin N is produced by eating foods rich in proteins and vitamin B1 (thiamine), however, as the aging proceeds, acid synthesis deteriorates.